Tuesday, 4/5/2022

Gavin MeadowsFollow

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University

Shawnee State University

Major

Biology-Biological Sciences

Student Type

Undergraduate Student

Presentation Types

Oral Presentation

Keywords:

green tea, cancer, leukemia, matcha

Abstract

Acute myeloid leukemia (AML) is a cancer of the bone marrow and blood that targets the body’s myeloblasts, red blood cells, and platelets, leading to anemia and weakness. These non-functional cancerous cells will continue to multiply and inhibit the function of healthy cells. This will eventually lead to immune system failure and other complications. AML has affected approximately twenty thousand individuals in 2021 alone and the five-year relative survival rate for this disease from 2011-2017 was a mere 29.5%. As a result, new treatment options are paramount. Our data has shown an inverse relationship with AML cell proliferation and the concentration of Matcha green tea (MGT). We have also observed cell death with high doses of MGT. Future research will focus on the mechanisms of MGT effects and what components of the tea influence these results.

Human Subjects

no

IRB Approval

no

Faculty Mentor Name

Dr. Jennifer Napper

Faculty Mentor Title

Associate Professor of Biology

Faculty Mentor Academic Department

Natural Sciences

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Effects of Matcha Green Tea in Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a cancer of the bone marrow and blood that targets the body’s myeloblasts, red blood cells, and platelets, leading to anemia and weakness. These non-functional cancerous cells will continue to multiply and inhibit the function of healthy cells. This will eventually lead to immune system failure and other complications. AML has affected approximately twenty thousand individuals in 2021 alone and the five-year relative survival rate for this disease from 2011-2017 was a mere 29.5%. As a result, new treatment options are paramount. Our data has shown an inverse relationship with AML cell proliferation and the concentration of Matcha green tea (MGT). We have also observed cell death with high doses of MGT. Future research will focus on the mechanisms of MGT effects and what components of the tea influence these results.