Metformin Treatment of Acute Myeloid Leukemia Cells

University

Shawnee State University

Major

Biology

Student Type

Undergraduate Student

Presentation Types

Oral Group Presentation

Keywords:

AML, Metformin, Cancer, Treatment

Abstract

Metformin is a regularly prescribed medication used to help reduce blood sugar levels within type 2 diabetics. Recent studies have indicated that patients taking Metformin long-term had an overall 31% reduction in cancer risk and cancer related mortality. Recent studies have attributed this effect to the anti-proliferative property when applied to the treatment of cultured cancer cells. However, the mechanism for this action is still elusive. Studies have not been conducted using Acute Myeloid Leukemia (AML) to date. Thus, the aim of our research is to determine Metformin’s effects when applied to AML while uncovering a mechanism of action. Therefore, closing a small gap in cancer research.

Faculty Mentor Name

Jennifer Napper

Faculty Mentor Title

Associate Professor

Faculty Mentor Academic Department

Natural Sciences

Location

LIB 204

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Mar 28th, 10:00 AM Mar 28th, 10:50 AM

Metformin Treatment of Acute Myeloid Leukemia Cells

LIB 204

Metformin is a regularly prescribed medication used to help reduce blood sugar levels within type 2 diabetics. Recent studies have indicated that patients taking Metformin long-term had an overall 31% reduction in cancer risk and cancer related mortality. Recent studies have attributed this effect to the anti-proliferative property when applied to the treatment of cultured cancer cells. However, the mechanism for this action is still elusive. Studies have not been conducted using Acute Myeloid Leukemia (AML) to date. Thus, the aim of our research is to determine Metformin’s effects when applied to AML while uncovering a mechanism of action. Therefore, closing a small gap in cancer research.